
*TMB and MSI reported in FoundationOne® CDx and FoundationOne® Liquid CDx.
†Therapies contained in the report may have been approved through a centralised EU procedure or a national procedure in an EU Member State.
‡ Analytical validation based on demonstrated concordance with the following companion diagnostics: cobas® EGFR Mutation Test, Ventana ALK (D5F3) CDx Assay, Vysis ALK Break-Apart FISH Probe Kit, therascreen® KRAS RGQ PCR Kit, Dako HER2 FISH PharmDx® Kit, cobas® BRAF V600 Mutation Test, THxID® BRAF kit.
For more information, please see the FoundationOne® CDx Technical Specifications [Hyperlink to CDx Tech Specs] and the FoundationOne® Liquid CDx Technical Specifications [Hyperlink to Liquid Tech Specs].
CGP: comprehensive genomic profiling; EMA: European Medicines Agency; FISH: fluorescence in situ hybridisation; IHC: immunohistochemistry; MAF: mutant allele fraction; MSI: microsatellite instability; NCCN: National Comprehensive Cancer Network; NGS: next-generation sequencing; NHS: National Health Service; PCR: polymerase chain reaction; TMB: tumour mutational burden.
M-GB-00001593 September 2020
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